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The five hundred and forty-sixth largest city in the United States, Saint Charles, Missouri is home to a population of just over 62,000 people. One of the oldest cities west of the Mississippi River; Saint Charles' economy revolves around construction, professional services, transportation, hospitality, education, and health care. The city is served by a number of large medical facilities, including Barnes-Jewish St. Peters Hospital, St. Joseph Health Center, and All Saints Special Care Hospital. Submit your resume to be matched to jobs in Saint Charles.